publications

Liu Y, Olsson A, Larva T, Cantwell-Jones A, Gill RJ, Cederberg B, Webster MT (2023). Genomic variation in montane bumblebees in Scandinavia: High levels of intraspecific diversity despite population vulnerability. Mol Ecol. e17251

Everitt T, Wallberg A, Christmas MJ, Olsson A, Hoffmann W, Neumann P, Webster MT (2023). The Genomic Basis of Adaptation to High Elevations in Africanized Honey Bees. Genome Biol Evol. 15(9):evad157.

Webster MT, Beaurepaire A, Neumann P, Stolle E (2023). Population genomics for insect conservation. Annu Rev Anim Biosci. 11: 115-140

Dyrhage K, Garcia-Montaner A, Tamarit D, Seeger C, Näslund K, Olofsson TC, Vasquez A, Webster MT, Andersson SGE (2022). Genome evolution of a symbiont population for pathogen defense in honeybees. Genome Biol Evol. 14: evac153

Christmas MJ, Jones JC, Olsson A, Wallerman O, Bunikis I, Kierczak M, Whitley KM, Sullivan I, Geib JC, Miller-Struttmann NE, Webster MT (2022). A genomic and morphometric analysis of alpine bumblebees: ongoing reductions in tongue length but no clear genetic component. Mol Ecol. 31: 1111-1127

Sánchez-Donoso I, Ravagni S, Rodríguez-Teijeiro JD, Christmas MJ, Huang Y, Maldonado-Linares A, Puigcerver M, Jiménez-Blasco I, Andrade P, Gonçalves D, Friis G, Roig I, Webster MT, Leonard JA, Vilà C (2022). Massive genome inversion drives coexistence of divergent morphs in common quails. Curr Biol. 32: 462-469

Christmas MJ, Jones JC, Olsson A, Wallerman O, Bunikis I, Kierczak M, Peona V, Whitley KM, Larva T, Suh A, Miller-Struttmann NE, Geib JC, Webster MT. (2021) Genetic barriers to historical gene flow between cryptic species of alpine bumblebees revealed by comparative population genomics. Mol Biol Evol. 38: 3126-3143.

Montero-Mendieta S, De la Riva I, Irisarri I, Leonard JA, Webster MT, Vilà C. (2021) Phylogenomics and evolutionary history of Oreobates (Anura: Craugastoridae) Neotropical frogs along elevational gradients. Mol Phylogenet Evol. 161:107167.

Webster MT. (2020) Population Genomics: How Do Cape Honey Bees Do Without Sex? Curr Biol. 2020 Jul 20;30(14):R820-R821.

Lamichhaney S, Han F, Webster MT, Grant BR, Grant PR, Andersson L. (2020) Female-biased gene flow between two species of Darwin's finches. Nat Ecol Evol. 2020 Jul;4(7):979-986.

Webster MT. (2019) Genome of the month: Apis mellifera. Trends Genet. 35:880-881.

Kawakami T, Wallberg A, Olsson A, Wintermantel D, de Miranda JR, Allsopp M, Rundlöf M, Webster MT. (2019) Substantial Heritable Variation in Recombination Rate on Multiple Scales in Honeybees and Bumblebees. Genetics. 212:1101-1119.

Jones JC, Wallberg A, Christmas MJ, Kapheim KM, Webster MT. (2019) Extreme Differences in Recombination Rate between the Genomes of a Solitary and a Social Bee. Mol Biol Evol. 36:2277-2291.

Christmas MJ, Smith NMA, Oldroyd BP, Webster MT. (2019) Social Parasitism in the Honeybee (Apis mellifera) Is Not Controlled by a Single SNP. Mol Biol Evol. 36:1764-1767.

Wallberg A, Bunikis I, Pettersson OV, Mosbech MB, Childers AK, Evans JD, Mikheyev AS, Robertson HM, Robinson GE, Webster MT. (2019) A hybrid de novo genome assembly of the honeybee, Apis mellifera, with chromosome-length scaffolds. BMC Genomics. 20:275.

Montero-Mendieta S, Tan K, Christmas MJ, Olsson A, Vilà C, Wallberg A, Webster MT. (2019) The genomic basis of adaptation to high-altitude habitats in the Eastern honey bee (Apis cerana). Mol Ecol. 28:746-760.

Christmas MJ, Wallberg A, Bunikis I, Olsson A, Wallerman O, Webster MT. (2019) Chromosomal inversions associated with environmental adaptation in honeybees. Mol Ecol. 28:1358-1374.

Henriques D, Parejo M, Vignal A, Wragg D, Wallberg A, Webster MT, Pinto MA. (2018) Developing reduced SNP assays from whole-genome sequence data to estimate introgression in an organism with complex genetic patterns, the Iberian honeybee (Apis mellifera iberiensis). Evol Appl. 11:1270-1282.

Henriques D, Wallberg A, Chávez-Galarza J, Johnston JS, Webster MT, Pinto MA. (2018) Whole genome SNP-associated signatures of local adaptation in honeybees of the Iberian Peninsula. Sci Rep. 8:11145.

Makino T, Rubin CJ, Carneiro M, Axelsson E, Andersson L, Webster MT. (2018) Elevated proportions of deleterious genetic variation in domestic animals and plants. Genome Biol Evol. 10:276-290.

Lamichhaney S, Han F, Webster MT, Andersson L, Grant BR, Grant PR. (2018) Rapid hybrid speciation in Darwin’s finches. Science 359:224-228.

Montero-Mendieta S, Grabherr M, Lantz H, De la Riva I, Leonard JA, Webster MT, Vilà C. (2017) A practical guide to build de-novo assemblies for single tissues of non-model organisms: the example of a Neotropical frog. PeerJ. 5:e3702.

Wallberg A, Schöning C, Webster MT, Hasselmann M. (2017) Two extended haplotype blocks are associated with adaptation to high altitude habitats in East African honey bees. PLoS Genet. 13(5):e1006792.

Han F, Lamichhaney S, Grant BR, Grant PR, Andersson L, Webster MT. (2017) Gene flow, ancient polymorphism, and ecological adaptation shape the genomic landscape of divergence among Darwin's finches. Genome Res. 27(6):1004-1015.

Nelson RM, Wallberg A, Simões ZLP, Lawson DJ, Webster MT. (2017) Genomewide analysis of admixture and adaptation in the Africanized honeybee. Mol Ecol. 26(14):3603-3617

Gilks WP, Pennell TM, Flis I, Webster MT, Morrow EH. (2016) Whole genome resequencing of a laboratory-adapted Drosophila melanogaster population sample. F1000Res. 5:2644.

Wallberg A, Pirk CW, Allsopp MH, Webster MT. (2016). Identification of Multiple Loci Associated with Social Parasitism in Honeybees. PLoS Genet. 9;12(6):e1006097.

Lamichhaney S, Han F, Berglund J, Wang C, Almén MS, Webster MT, Grant BR, Grant PR, Andersson L. (2016). A beak size locus in Darwin’s finches facilitated character displacement during a drought. Science 352(6284):470-4.

Almén MS, Lamichhaney S, Berglund J, Grant BR, Grant PR, Webster MT, Andersson L. (2016). Adaptive radiation of Darwin's finches revisited using whole genome sequencing. Bioessays 38:14-20.

Webster MT, Kamgari N, Perloski M, Hoeppner MP, Axelsson E, Hedhammar Å, Pielberg G, Lindblad-Toh K. (2015). Linked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds. BMC Genomics 16:474.

Wallberg A, Glémin G, Webster MT. (2015). Extreme recombination frequencies shape genome variation and evolution in the honeybee, Apis mellifera. PLoS Genet. 11(4):e1005189.

Lamichhaney S, Berglund J, Sällman Almén M, Maqbool K, Grabherr M, Martinez-Barrio A, Promerová M, Rubin CJ, Wang C, Zamani N, Grant BR, Grant PR, Webster MT, Andersson L. (2015). Evolution of Darwin's finches and their beaks revealed by genome sequencing. Nature 518:371-5.

Berglund J, Quilez J, Arndt PF, Webster MT. (2014). Germline methylation patterns determine the distribution of recombination events in the dog genome. Genome Biol Evol 7:522-30.

Wallberg A, Han F, Wellhagen G, Dahle B, Kawata M, Haddad N, Simoes ZLP, Allsopp MH, Kandemir I, De la Rua P, Pirk CW, Webster MT. (2014) A worldwide survey of genome sequence variation provides insight into the evolutionary history of the honeybee Apis mellifera. Nat Genet. 46: 1081-1088

Ramirez O, Olalde I, Berglund J, Lorente-Galdos B, Hernandez-Rodriguez J, Quilez J, Webster MT, Wayne RK, Lalueza-Fox C, Vila C, Marques-Bonet T. (2014) Analysis of structural diversity in wolf-like canids reveals post-domestication variants. BMC Genomics. 15:465.

Molin AM, Berglund J, Webster MT, Lindblad-Toh K. (2014) Genome-wide copy number variant discovery in dogs using the CanineHD genotyping array. BMC Genomics. 15:210

Borge KS, Melin M, Rivera P, Thoresen SI, Webster MT, von Euler H, Lindblad-Toh K, Lingaas F. (2013) The ESR1 gene is associated with risk for canine mammary tumours. BMC Vet Res. 9:69.

Axelsson E, Ratnakumar A, Arendt ML, Maqbool K, Webster MT, Perloski M, Liberg O, Arnemo JM, Hedhammar A, Lindblad-Toh K. (2013) The genomic signature of dog domestication reveals adaptation to a starch-rich diet. Nature 495(7441):360-4.

Rands CM, Darling A, Fujita M, Kong L, Webster MT, Clabaut C, Emes RD, Heger A, Meader S, Hawkins MB, Eisen MB, Teiling C, Affourtit J, Boese B, Grant PR, Grant BR, Eisen JA, Abzhanov A, Ponting CP. (2013) Insights into the evolution of Darwin's finches from comparative analysis of the Geospiza magnirostris genome sequence. BMC Genomics 14:95.

Webster MT, Hurst LD. (2012) Direct and indirect consequences of meiotic recombination: implications for genome evolution. Trends Genet. 28(3):101-9.

Owczarek-Lipska M, Lauber B, Molitor V, Meury S, Kierczak M, Tengvall K, Webster MT, Jagannathan V, Schlotter Y, Willemse T, Hendricks A, Bergvall K, Hedhammar A, Andersson G, Lindblad-Toh K, Favrot C, Roosje P, Marti E, Leeb T. (2012) Two loci on chromosome 5 are associated with serum IgE levels in Labrador retrievers. PLoS One. 7(6):e39176.

Berglund J, Nevalainen EM, Molin AM, Perloski M; The LUPA Consortium, André C, Zody MC, Sharpe T, Hitte C, Lindblad-Toh K, Lohi H, Webster MT. (2012) Novel origins of copy number variation in the dog genome. Genome Biol. 13(8).

Han F, Wallberg A, Webster MT. (2012) From where did the Western honeybee (Apis mellifera) originate? Ecol Evol. 2012 Aug;2(8):1949-57.

Lamichhaney S, Martinez Barrio A, Rafati N, Sundström G, Rubin CJ, Gilbert ER, Berglund J, Wetterbom A, Laikre L, Webster MT, Grabherr M, Ryman N, Andersson L. (2012) Population-scale sequencing reveals genetic differentiation due to local adaptation in Atlantic herring. Proc Natl Acad Sci U S A. 109(47):19345-50.

Larson G, Karlsson EK, Perri A, Webster MT, Ho SY, Peters J, Stahl PW, Piper PJ, Lingaas F, Fredholm M, Comstock KE, Modiano JF, Schelling C, Agoulnik AI, Leegwater PA, Dobney K, Vigne JD, Vilà C, Andersson L, Lindblad-Toh K. (2012) Rethinking dog domestication by integrating genetics, archeology, and biogeography. Proc Natl Acad Sci U S A. 109(23):8878-83.

Axelsson E, Webster MT. (2011) Base Composition Patterns. Encyclopedia of Life Sciences.

Axelsson E, Webster MT, Ratnakumar A, Consortium L, Ponting CP, Lindblad-Toh K. (2011) Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome. Genome Res. 22(1):51-63.

Vaysse A, Ratnakumar A, Derrien T, Axelsson E, Rosengren Pielberg G, Sigurdsson S, Fall T, Seppälä EH, Hansen MS, Lawley CT, Karlsson EK; The LUPA Consortium, Bannasch D, Vilà C, Lohi H, Galibert F, Fredholm M, Häggström J, Hedhammar A, André C, Lindblad-Toh K, Hitte C, Webster MT. (2011) Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping. PLoS Genet. 7(10):e1002316.

Seppälä EH, Jokinen TS, Fukata M, Fukata Y, Webster MT, Karlsson EK, Kilpinen  SK, Steffen F, Dietschi E, Leeb T, Eklund R, Zhao X, Rilstone JJ, Lindblad-Toh K, Minassian BA, Lohi H. (2011) LGI2 truncation causes a remitting focal epilepsy in dogs. PLoS Genet. 7(7):e1002194.

Mausberg TB, Wess G, Simak J, Keller L, Drögemüller M, Drögemüller C, Webster MT, Stephenson H, Dukes-McEwan J, Leeb T. (2011) A locus on chromosome 5 is associated with dilated cardiomyopathy in Doberman Pinschers. PLoS One. 6(5):e20042.

Olsson M, Meadows JR, Truvé K, Rosengren Pielberg G, Puppo F, Mauceli E, Quilez J, Tonomura N, Zanna G, Docampo MJ, Bassols A, Avery AC, Karlsson EK, Thomas A, Kastner DL, Bongcam-Rudloff E, Webster MT, Sanchez A, Hedhammar A, Remmers EF, Andersson L, Ferrer L, Tintle L, Lindblad-Toh K. (2011) A novel unstable duplication upstream of HAS2 predisposes to a breed-defining skin phenotype and a periodic fever syndrome in Chinese Shar-Pei dogs. PLoS Genet. 7(3):e1001332.

Ratnakumar A, Mousset S, Glémin S, Berglund J, Galtier N, Duret L, Webster MT. (2010) Detecting positive selection within genomes: the problem of biased gene conversion. Philos Trans R Soc Lond B Biol Sci. 365:2571-80.

Rubin CJ, Zody MC, Eriksson J, Meadows JR, Sherwood E, Webster MT, Jiang L, Ingman M, Sharpe T, Ka S, Hallböök F, Besnier F, Carlborg Ö, Bed'hom B, Tixier-Boichard M, Jensen P, Siegel P, Lindblad-Toh K, Andersson L. (2010) Whole-genome resequencing reveals loci under selection during chicken domestication. Nature 25:587-91.

Bannasch D, Young A, Myers J, Truvé K, Dickinson P, Gregg J, Davis R, Bongcam-Rudloff E, Webster MT, Lindblad-Toh K, Pedersen N. (2010) Localization of canine brachycephaly using an across breed mapping approach. PLoS ONE 5:e9632.

Backström N, Forstmeier W, Schielzeth H, Mellenius H, Nam K, Bolund E, Webster MT, Öst T, Schneider M, Kempenaers B, Ellegren H. (2010) The recombination landscape of the zebra finch Taeniopygia guttata genome. Genome Res 20:485-95.

Webster MT, Karlsson EK (2009) Evolution of the dog genome. Encyclopedia of Life Sciences.

Webster MT. (2009) Patterns of autosomal divergence between the human and chimpanzee genomes support an allopatric model of speciation. Gene 443:70-5.

Berglund J, Pollard KS, Webster MT. (2009) Hotspots of biased nucleotide substitutions in human genes. PLoS Biology 7:e26.  (also Featured in News & Views, Nature 457:543-4)

Cruz F, Vila C, Webster MT. (2008) The legacy of domestication: accumulation of deleterious mutations in the dog genome. Mol Biol Evol 25: 2331-6.

Webster MT. (2008) Human-specific accelerated evolution of noncoding sequences. Encyclopedia of Life Sciences. (updated version published 2013)

Mank, JE, Hultin-Rosenberg L, Webster MT, Ellegren H. (2008) The unique genomic properties of sex-biased genes: insights from avian microarray data. BMC Genomics 9:148.

Webster MT, Hagberg J. (2007) Is there evidence for convergent evolution around human microsatellites? Mol Biol Evol 24:1097-100.

Björnerfeldt S, Webster MT. (joint first authors), Vila C (2006). Relaxation of selective constraint on dog mitochondrial DNA following domestication. Genome Res 16:990-4

Webster MT, Axelsson E, Ellegren H. (2006). Strong regional biases in nucleotide substitution in the chicken genome. Mol Biol Evol 23:1203-16.

Borge T, Webster MT, Andersson G, Saetre GP. (2005). Contrasting patterns of polymorphism and divergence on the Z chromosome and autosomes in two Ficedula flycatcher species. Genetics 171:1861-73.

Webster MT, Smith NGC, Hultin-Rosenberg L, Arndt PF, Ellegren H. (2005). Male-driven biased gene conversion governs the evolution of base composition in human Alu repeats. Mol Biol Evol 22:1468-1474.

Belle EMS, Webster MT, Eyre-Walker A. (2005). How can we explain the differential distribution of young and old repeats in the human genome? J Mol Evol 60:290-296.

Axelsson E, Webster MT, Smith NGC, Burt DW, Ellegren H. (2005). Comparison of the chicken and turkey genomes reveals a higher rate of nucleotide divergence on microchromosomes than macrochromosomes. Genome Res 15:120-5.

International Chicken Genome Sequencing Consortium. (2004). Sequencing and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432:695-716.

Webster MT, Smith NGC, Lercher MJ, Ellegren H. (2004). Gene expression, synteny, and local similarity in human noncoding mutation rates. Mol Biol Evol 21:1820-30.

Sundstrom H, Webster MT, Ellegren H. (2004). Reduced variation on the chicken Z chromosome. Genetics 167:377-85.

Webster MT, Smith NGC. (2004). Fixation biases affecting human SNPs. Trends Genet 20:122-6.

Ellegren H., Smith NGC, Webster MT. (2003). Mutation rate variation in the mammalian genome. Curr Opin Genet Dev 13:562-8.

Webster MT, Clegg JB, Harding RM. (2003). Common 5' beta-globin RFLP haplotypes harbour a surprising level of ancestral sequence mosaicism. Hum Genet 113:123-39.

Sundstrom H, Webster MT, Ellegren H. (2003). Is the rate of insertion and deletion mutation male-biased? Molecular evolutionary analysis of avian and primate sex chromosome sequences. Genetics 164:259-68.

Webster MT, Smith NGC, Ellegren H. (2003). Compositional evolution of the human and chimpanzee genomes. Mol Biol Evol 20:278-86.

Smith NGC, Webster MT, Ellegren H. (2003). A low rate of simultaneous double nucleotide mutations in primates. Mol Biol Evol 20:47-53.

Smith NGC, Webster MT, Ellegren H. (2002). Deterministic mutation rate variation in the human genome. Genome Res 12:1350-6.

Webster MT, Smith NGC, Ellegren H. (2002). Microsatellite evolution inferred from human-chimpanzee genomic sequence alignments. Proc Natl Acad Sci U S A 99:8748-53.

Webster MT, Wells RS, Clegg JB. (2002). Analysis of variation in the human beta-globin gene cluster using a novel DHPLC technique. Mutat Res 501:99-103.

Wells RS, Yuldasheva N, Ruzibakiev R, Underhill PA, Evseeva I, Blue-Smith J, Jin L, Su B, Pitchappan R, Shanmugalakshmi S, Balakrishnan K, Read M, Pearson NM, Zerjal T, Webster MT, Zholoshvili I, Jamarjashvili E, Gambarov S, Nikbin B, Dostiev A, Aknazarov O, Zalloua P, Tsoy I, Kitaev M, Mirrakhimov M, Chariev A and Bodmer WF. (2001). The Eurasian heartland: a continental perspective on Y-chromosome diversity. Proc Natl Acad Sci U S A 98:10244-9.

Rees DC, Chapman NH, Webster MT, Guerreiro JF, Rochette J, Clegg JB. (1999). Born to clot: the European burden. Br J Haematol 105:564-6.